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In vitro permeation research suggested that the microneedles delivered 74.7percent of the drug load over 6 h, which exhibited remarkable drug permeation properties in a short time. Right here, we creatively blended micellar technology with microneedle technology to quickly provide Cur transdermally for diseases treatment such as for instance melanoma. Graphical abstract.Following skin injury, the overproduction of reactive oxygen types (ROS) during the i