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After 24 h, biofilms induced weak inflammatory reaction when you look at the peri-implant mucosa by upregulation of 5 genetics associated with immune response and enhanced secretion of IL-6 and CCL20. Biofilm volume had been reduced that will be explained by secretion of β-Defensins-1, -2, and CCL20. The specific muscle response without intrinsic overreaction might subscribe to undamaged mucosa. Therefore, a relationship similar to homeostasis and oral health was founded insid