https://pai1signal.com/index.p....hp/potential-screeni
© 2020. Published by The business of Biologists Ltd.The mitochondrial DNA of Trypanosoma brucei and related parasites is a catenated community containing numerous of minicircles and tens of maxicircles called kinetoplast DNA (kDNA). Replication of this single nucleoid requires at least three DNA polymerases (POLIB, POLIC, and POLID) each having discrete localization nearby the kDNA during S stage. POLIB and POLID have roles in minicircle replication as the specific role of POLIC in kD