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erformed simulations, which provided useful information for the application of Dracaena angustifolia Roxb in diabetes treatment. Despite their mild effects on α-amylase, considerable α-glucosidase inhibitory efficiencies and potential synergy with acarbose were exhibited by these natural candidates. Furthermore, a stable ligand, human α-glucosidase, was predicted by the performed simulations, which provided useful information for the application of Dracaena angustifolia Roxb in diabetes treatment. Norepinephrine (NE) is a α -adrenergic