https://miransertibinhibitor.c....om/presenting-along-
Extensive protection by N-glycans on top associated with HIV-1 Env acts as an immune evasion apparatus by restricting B mobile recognition of conserved neutralizing determinants. An alternate method is to design Env necessary protein with glycan removal to expose the necessary protein surface. A well balanced native-like trimeric Env with glycan holes at potentially immunogenic areas is expected to generate better induction of germ-line B-cells due to publicity of the immunogenic areas. Nonetheless