https://www.selleckchem.com/products/gdc-0068.html
Diet-induced obesity (DIO) is considered the main risk factor for cardiovascular diseases. Increases in the plasma levels of tumor necrosis factor alpha (TNF-α) is associated with DIO. Etanercept, a TNF-α inhibitor, has been shown to alleviate cardiac hypertrophy. To investigate the effect of etanercept on cardiac fibrosis in DIO model, rats on high fat diet (HFD) were subdivided into two groups the etanercept group and vehicle group. Cardiac injury was identified by classic methods, while fibrosis was characterized by histological ana
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