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Treatment For ADHD The most effective treatment options for add are medications and psychosocial therapy (psychotherapy). These medications include stimulants like amphetamine and methylphenidate, and non-stimulants like atomoxetine and viloxazine, guanfacine, clonidine and gu. Patients with active substance abuse issues should not take stimulant medications. However, those who are in stable remission might take them into consideration. Comb