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The most important factors in early prediction were related to student assessment and data obtained from student interaction with Learning Management Systems. Finally, how early it was possible to make predictions depended on the type of educational system. Most of the papers analyzed were about online learning systems and traditional face-to-face learning in secondary and tertiary education; the most commonly-used predictive algorithms were J48, Random Forest, SVM, and Naive Bayes (classification), and logistic and linear

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Despite the high effectiveness of direct-acting antivirals for the treatment of hepatitis C, a small proportion of patients do not respond to approved regimens. The combination regimen of SOF/VEL/VOX was recently approved for patients with failure to prior NS5A-based treatment. In this German real-world cohort including patients with cirrhosis (27.3 %) and previous decompensation events, 12 weeks of SOF/VEL/VOX resulted in high virologic response rates irrespective of disease severity and prior DAA regimen. Adverse events were mostly mi