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ns (OR, 2.98; 95% CI, 1.16-7.69) were related to PDD. Conclusions Cognitive impairment in PD is associated with more severe disease stage, resulting in a global, neuropsychiatric, psychosocial, and quality-of-life deterioration. This study provides a better understanding of the great impact that cognitive impairment has within the natural history of PD and its relationship with the rest of motor and non-motor symptoms in the disease.Objective We aimed to utilize the data on lifetime risk of stroke, from Global Burden of Disease (GBD) 20