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ADHD in Adults Treatment ADHD is linked to significant impairments of academic performance and social functioning. Adults who suffer from ADHD are at a higher risk of developing anxiety disorders, depression and abuse of substances. The medications that help improve ADHD symptoms by increasing neurotransmitters that regulate attention and impulsivity seem to be working. Medication trials are conducted to determine which medications are most effective and in what dos

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Functionally, STK39 inhibition markedly impaired the EMT phenotype and decreased tumor cell migration, invasion, and metastasis both in vitro and in vivo. These effects were rescued by ectopic SNAI1 expression. In addition, depletion of STK39 dramatically enhanced sensitivity to chemotherapeutic agents. Conclusions Our study demonstrated that STK39 is a key mediator of SNAI1 stability and is associated with the pro-metastatic cellular process, highlighting the STK39-SNAI1 signaling axis as promising therapeutic targets