https://www.selleckchem.com/pr....oducts/sabutoclax.ht
ly, and the efficacy of folinate with respect to protecting against such depletion deserves to be evaluated in medical practice.4-Hydroxynonenal (HNE) is a major aldehydic product of lipid peroxidation known to exert several biological effects. Normal and malignant cells of the same origin express different sensitivity to HNE. We used human osteosarcoma cells (HOS) in different stages of differentiation in vitro, showing differences in mitosis, DNA synthesis, and alkaline phosphatase (ALP) staining. Differentiated HOS cells showed de