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Stimulant Vs Non Stimulant ADHD Medication Stimulants are the most popular type of prescription medication that healthcare practitioners utilize to treat ADHD. These drugs target specific chemicals in the brain, like dopamine and norepinephrine to improve symptoms like the inability to focus and impulsivity. Nonstimulant medicines are second-line treatments for patients who don't respond to stimulants. They also have fewer side effects. They target different neurotran