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First Line Treatment For ADHD in Adults Some people with ADHD have found that medication can help manage their symptoms. The stimulants, like amphetamine and methylphenidate are effective in boosting activity in the brain regions that regulate the behavior and attention. Other medications, like the nonstimulant atomoxetine and some antidepressants, work differently but are also effective. Regular visits to the GP are recommended for people who take medication. They can