https://www.selleckchem.com/pr....oducts/bromodeoxyuri
The final exposure-response model, based on a generalized Poisson distribution and an inhibitory E relationship, adequately describes the relationship between daily emicizumab concentrations and daily bleed frequency. A significant effect of factor VIII prophylaxis among persons with hemophilia A without inhibitors was found. Annualized bleeding rate simulations show that the three emicizumab dosing regimens maintain the concentrations close to the plateau of the effect. At the average steady-state concentration across al