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What is the Best Treatment For ADHD in Adults? The majority of people suffering from ADHD benefit from a mix of treatments. Those treatments are typically multimodal and include treatment, medication and lifestyle modifications. Stimulants are the most popular treatment for ADHD. Finding the right dosage and balancing the side effects can be a tinkering procedure. Atomoxetine is an FDA-approved non-stimulant that does not have the potential for abuse of stimulants