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The metabolisms various stages had been driven by different microorganisms. Overall, these findings deepened our comprehension of metabolic features, and it's also of great worth into the metabolomics research of composting system. BACKGROUND Duloxetine administered during the acute perioperative period has been involving cheaper postoperative pain and analgesic consumption. RESEARCH OBJECTIVES The study aimed to quantify the pooled ramifications of duloxetine on postoper