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Lower physical activity has been cross-sectionally associated with greater perceived fatigability, defined as self-reported fatigue anchored to activity intensity and duration. The temporality of this relationship, and whether it differs by activity type or marital status, remains unclear. In the Osteoporotic Fractures in Men Study (MrOS; N=1,759), self-reported total, exercise, and household activity were assessed using the Physical Activity Scale for the Elderly across seven visits (2000-2016). The Pittsburgh Fatigability Scale (ra