https://www.selleckchem.com/pr....oducts/dt-061-smap.h
Chrysomycin A (CA) has been reported as numerous excellent biological activities, such as antineoplastic and antibacterial. Though, poor solubility of CA limited its application in medical field. Due to good amphiphilicity and potential anticancer effect of disodium glycyrrhizin (Na GA) as an excipient, an amorphous solid dispersion (Na GA/CA-BM) consisting of CA and Na GA was prepared in the present study by mechanochemical technology (roll mill ML-007, zirconium balls, 30rpm, 2.5h) to improve the solubility and oral bioavailabilit