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ADHD Treatment For Adults - Stimulant Medication Stimulant drugs like methylphenidate and dextroamphetamine are generally considered as the first line treatment for adults with ADHD. These drugs increase and balance brain chemicals called neurotransmitters. Nonstimulant medications such as atomoxetine or antidepressants can be prescribed if stimulants aren't appropriate for the patient due to other health issues or side effects. These medications