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ity to various infectious agents with disparate geographic distributions within the United States. The incidence and prevalence of infectious uveitis/scleritis in the United States were higher than previously reported estimates but remained lower than in developing countries. Rates varied by age, sex, race, and medical comorbidities, and may reflect differential susceptibility to various infectious agents with disparate geographic distributions within the United States. We performed a cross-sectional study of HIV-uninfected men and wom