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The Ginkgo biloba L. tree is considered as one of the oldest species on Earth. It is known as a "living fossil" dating back approximately 200 million years. Both the leaves and seeds of this tree have been used for millennia in traditional Chinese medicine. To study the phytochemical profile of Gingko biloba seed extract (GBSE) and its memory enhancing effects. Liquid chromatography with mass detection (LC-MS) was performed for phytochemical analyses of the extracts. For the in vivo experiments, male Wistar rats were divided randomly in