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How Does Medication For ADHD Work? Stimulants enhance your ability to concentrate and control impulses by increasing the levels dopamine and norepinephrine within your brain. They are available in immediate-release (short acting) and extended release tablets, which are taken every day in the morning. Nonstimulant medications take longer to work but can also improve attention and impulse control. Atomoxetine (Strattera) and guanfacine (Viloxazine) are both in the antidepressant class and boost levels o