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Outcomes JADER included 366,501 cases with all the unfavorable events of great interest; 4322 involved SGLT2 inhibitors. The ROR for SGLT2 inhibitors ended up being determined as 1.0 (95% CI 0.9-1.2) for ARF, 72.2 (95% CI 59.3-87.8) for ketoacidosis, and 14.0 (95% CI 11.0-17.8) for UTIs. Evaluation of only subjects obtaining treatment plan for diabetes showed the same trend. Conclusion The results proposed a correlation between SGLT2 inhibitors in addition to onset of keto