https://www.selleckchem.com/pr....oducts/ldn-212854.ht
5-fluorouracil (5-FU) is one of the most common causes of cardiotoxicity associated with chemotherapy. The manifestations of 5-FU cardiotoxicity are diverse, and there are no established clinical guidelines addressing the diagnosis and management of this condition. Here we summarize the mechanistic and clinical data available to guide clinicians in caring for patients with suspected 5-FU cardiotoxicity. The decision to resume 5-FU treatment in patients with suspected cardiovascular toxicity remains challenging. Testing for predisposi