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First Line Treatment For ADHD in Adults Certain people suffering from ADHD are able to use medications to manage their symptoms. like methylphenidate and amphetamine work by increasing brain activity in areas that regulate attention and behavior. Other medications, like the nonstimulant atomoxetine and some antidepressants, work differently but are also efficient. Regular visits to the GP are recommended for those who take medications. They can alter dosages and observe body reactions. Medication