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001). Small left ventricles with valves deemed proportional in size were found in 11 (42%) of those with combined mitral and aortic stenosis. Fibroelastosis was significantly more common in the hearts with mitral stenosis compared to those with mitral atresia (76% vs. 11%, p less then 0.001). The ascending aorta was significantly smaller in the hearts with aortic atresia. The variability in the morphological findings support the notion that the lesions seen represent acquired disease occurring subsequent to closure of the embryonic int