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701, 95% CI, 1.124-2.573, =0.012, I =34.7%). With regard to CT60 polymorphism, donors with G allele correlated with worse OS (HR = 1.422, 95% CI, 1.080-1.872, =0.012, I =0%) and lower susceptibility to severe acute GVHD (HR=0.619, 95% CI, 0.426-0.899, =0.012, I =0%). There was no significant association between CTLA-4 polymorphism and DFS or the incidence of relapse. The present meta-analysis suggests that donors with CT60 G allele might be associated with worse OS but reduced severe aGVHD occurrence, while patients transplanted from do