https://www.selleckchem.com/
In 2D, the cell growth rate of cells treated with AlgSulf was consistently lower compared to untreated controls (p less then 0.001) and surpassed the effect of the native GAG heparin (positive control). In 3D, AlgSulf preferentially hindered the growth rate and the invasion potential of tumorigenic T4-2 nodules while maintaining the formation of differentiated polarized nontumorigenic S1 acini. The preferential growth inhibition of tumorigenic cells by AlgSulf was confirmed in a coculture system (p less then 0.001). In the ELISA assay, a trend of EGF bindin