https://www.selleckchem.com/pr....oducts/bms-265246.ht
The highly innervated cornea is susceptible to nerve loss secondary to systemic diseases such as diabetes and metabolic disturbances caused by high-fat diet. In this study, we characterize the effect of high-fat diet on the mouse corneal neuroimmune phenotype, including changes to corneal nerve density and resident immune cells, alongside the clinical assessment of corneal thickness and endothelial cell density. Male C57Bl6/J mice, aged 10 weeks, were fed a high-fat diet (60kcal% fat, 5.2kcal/g) or control diet (10kcal%, 3.8kcal/g) f