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Moreover, contrast with other plants showed that monocots share a similar circulation of G4s, but Arabidopsis reveals a unique G4 distribution. Our research reveals for the first time the prevalence and feasible functional roles of G4s in wheat. Copyright © The Author(s) 2020. Published by the Genetics community of America.The evolutionarily conserved centromeric histone H3 variant (Cse4 in budding yeast, CENP-A in humans) is essential for faithful chromosome segregat