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Threat factors being identified and quantified, particularly it is now well recognized that among maternal major attacks only those occurring in the first trimester may lead to lasting sequelae. Algorithms combining IgG, IgM and IgG avidity detection with serological assays adapted on high throughput systems have shown large susceptibility and specificity to diagnose maternal major disease. The prognostic value of prenatal imaging combining ultrasound and MRI happens to be val

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035). Increased 25OHD concentration was associated with a decrease in delirium prevalence (OR = 0.99 [95CI 0.98-0.99] per nmol/L of 25OHD, p = 0.038). The concentration distinguishing between cases and controls with the best sensitivity-specificity was found between 29.5 and 30.5 nmol/L. The regression models showed that delirium was associated with hypovitaminosis D defined either as 25OHD ≤ 50 nmol/L (OR = 2.37 [95CI 1.07-5.25], p = 0.034) or as 25OHD ≤ 30 nmol/L (OR = 2.66 [95 CI 1.30-5.45], p = 0.008). Conclusions Decreased serum 25O