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The dominant deformation mode for the anisotropic Ti-6Al-4V columnar structure is basal slip, and that for the isotropic Ti-6Al-4V columnar structure is pyramidal slip. The difference may be important for determining the fatigue behaviour. Patients undergoing cardiopulmonary stabilization in the intensive care unit for novel coronavirus (COVID-19) are often sedated, placing timely assessment of a neurological decline at risk. Here, we present two cases of COVID-19 infected young patients transferred to our facility in a cardio-pulmonary