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The goal of this review is to examine the state-of-the-science in the areas of intuitive control and sensation of prosthetic devices and to discuss areas of exploration for the future. Current research and development efforts in external systems, implanted systems, surgical approaches, and regenerative approaches will be explored. © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2019.The socket is the most critical part of every lower-limb prosthetic system, since it s