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05). IL-5, IL-12, IL-15, IFN-γ and MIP-1a were significantly higher in aqueous humour of glaucoma eyes (p less then 0.05). A poor correlation between cytokine levels in tear and aqueous humour was observed. CONCLUSION The different profiles of inflammatory marker expression of patients with POAG and healthy controls confirm the inflammatory activity of the pathology, indicating that some of them could be used as potential biomarkers of this disease. © 2020 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley Sons