https://www.selleckchem.com/pr....oducts/xl413-bms-863
5 months vs. 20.0 months; hazard ratio, 1.63; 95% confidence interval, 1.43-1.85; P .0001) and worse overall survival (OS) (median OS, 23.2 months vs 39.3 months; hazard ratio, 1.51; 95% confidence interval, 1.30, 1.74; P .0001). Morbid PD occurs frequently and is associated with inferior second PFS and OS. As CRAB symptoms may not reverse with therapy, morbid PD is a meaningful event, and its association with a shortened PFS adds validity to PFS as a relevant endpoint in patients with MM. Morbid PD occurs frequently an