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21, 95% CI 1.05-4.6) and in those with cancer (OR 0.15, 95% CI 0.03-0.68) the PIMS risk was lower. The presence of comorbidities modifies the risk of infection by SARS-CoV-2 and PIMS. The presence of comorbidities modifies the risk of infection by SARS-CoV-2 and PIMS. Programmed restriction (PR) of antimicrobials can selectively decrease the rate of infections by certain microorganisms. In this sense, AmpC β-lactamase-producing gram-negative bacilli (GNB-blaAmpC) are selected for the overuse of third generation cephalo