https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
This brief review provides a comprehensive summary on the main sources of free radical damage, occurring in the setting of neurodegeneration.Biliverdin reductase-A (BVR) catalyzes the reduction of heme-derived biliverdin into bilirubin, this latter being a powerful endogenous free radical scavenger. Furthermore, BVR is also endowed with both serine/threonine/tyrosine kinase and scaffold activities, through which it interacts with the insulin receptor kinase, conventional and atypical protein kinase C isoforms, mitogen-activ