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Treatment For ADHD Psychosocial therapy is the most common treatment for adding. The medications can include stimulants such as methylphenidate and amphetamine, and non-stimulants like atomoxetine and viloxazine, guanfacine, and clonidine. Stimulant medications should not be used by patients who have active addiction issues, but they are an option for those who are in stable in remission. Combination therapy using antidepressants especially SSRIs, is a different option. Stimulants Stimulants increase dopamine and norepinephrine levels in the brain's synapses.