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l characteristics associated with T2DM and obvious renal lesions suggestive of kidney damage. Copyright © 2020 Liu, Huang, Gao and Liu.Studies in yeast first delineated the function of Mob proteins in kinase pathways that regulate cell division and shape; in multicellular eukaryotes Mobs regulate tissue growth and morphogenesis. In animals, Mobs are adaptors in Hippo signaling, an intracellular signal-transduction pathway that restricts growth, impacting the development and homeostasis of animal organs. Central to Hippo signali