https://www.selleckchem.com/pr....oducts/Rapamycin.htm
6 [0.14] to 2.5 [0.22]-fold of sham, P0.01) in injured DRG were time-dependently increased on days 3-14 after SNL. Blocking increased eIF4G2 through microinjection of eIF4G2 siRNA into the injured DRG attenuated SNL-induced downregulation of DRG MOR and Kv1.2 and development and maintenance of nociceptive hypersensitivities. DRG microinjection of AAV5-eIF4G2 reduced DRG MOR and Kv1.2 expression and elicited hypersensitivities to mechanical, heat and cold stimuli in naïve mice. eIF4G2 contributes to neuropathic pain through partici
Like
Comment
Share
