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This case of a patient with a significant history of caries, single-tooth restorations, and multiple extractions demonstrates the potential problems that may be associated with intermittent, single-tooth care and the importance of restorative clinicians thoroughly assessing the patient's medical and dental history. Patients may present with a failing biological system that could lead to unforeseen circumstances during treatment. When such a case presents itself, systematic and comprehensive risk assessment can play an instrumental role i