https://www.selleckchem.com/pr....oducts/incb054329.ht
These findings clearly emphasize that CTLA-4-Ig can effectively prevent podocyte damage, inhibiting inflammation and fibrosis, and thereby treating and preventing DN. In addition, ultrasound microbubble exposure can improve the ability of CTLA-4-Ig to pass through the glomerular basement membrane in order to access podocytes such that combination CTLA-4-Ig + microbubble exposure treatment is superior to treatment with CTLA-4-Ig only. These findings clearly emphasize that CTLA-4-Ig can effectively prevent podocyte damage, inhibiting i

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