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Treatment For Add ADHD in Adults Adults with add adhd are typically treated with a combination of medication, education, and training in skills. It can also include family therapy and cognitive-behavioral therapy (CBT). Methylphenidate, the most common stimulant used to treat ADHD in adults, works by increasing brain activity. It stimulates the brain regions that regulate the behavior and attention. It is available in immediate-release and extended-release tablets. Medicatio