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This review focuses on the detailed anatomy associated with the pain-signaling pathway together with roles of chemicals in inducing different systems of LBP. MRI findings that serve as representative samples of crucial ideas tend to be shown in accordance with each mechanism, and treatment options are reviewed on such basis as various factors that cause LBP. By knowing these principles, radiologists can help associate imaging results with possible fundamental mechanisms and help guid

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We also demonstrate that the impact of the cytotoxic agent cytarabine is selectively enhanced by a high-potency statin. The cholesterol biosynthesis programme is amenable to additional translational opportunities within the expanding AML therapeutic landscape. Our findings support the further investigation of higher-potency statin (eg rosuvastatin)-based combination therapies to enhance targeting residual AML cells that reside in low O2 environments.Introduction To create and clinically validate knowledge-based planning (KBP) models fo