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Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two ends of the same disease spectrum of adult-onset neurodegenerative diseases that affect the motor and cognitive functions, respectively. Multiple common genetic loci such as fused in sarcoma (FUS) have been identified to play a role in ALS and FTD etiology. Current studies indicate that FUS mutations incur gain-of-toxic functions to drive ALS pathogenesis. However, how the disease-linked mutations of FUS affect cognition remains elusive. Using a mouse mod

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Portable Scooter A portable scooter is a model that can be disassembled and divided into a number of pieces for easy transportation. It is a good option for those who travel often. These scooters are able to fit into the trunks of most vehicles. They also tend to be lighter than larger mobility scooters. The majority of them have wheels made of foam or solid that won't be flat. Easy to transport If you want to to travel and go out with friends, you'll require mobility scooters that are easy to transport. These portable