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ement strategies. Our results point to important roles of miRNA-mediated regulation of ascaroside function in insect cold adaptation. This enhanced cold tolerance may allow higher survival of M. alternatus in winter and be pivotal in shaping its wide distribution range, greatly expanding the threat of pine wilt disease, and thus can also inspire the development of ascaroside-based pest management strategies.An amendment to this paper has been published and can be accessed via the original article. Hepatic portal venous gas (HPVG) is a rare clinica
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