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Everytime after infusion, the automobile T-cells underwent excessively fast exponential growth, which can be as a result of the disturbance of TP53, a gene that will functionally get a grip on cellular pattern arrest. Level 4 and quality 1 cytokine release problem happened after the very first and second rounds of CAR T-cell treatment, respectively. CONCLUSIONS This instance supplies the first report for the usage of CAR T-cell treatment in a hematologic malignancy patient with LFS. As traditional chemot