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How Does ADHD Medication Work? The medications can reduce ADHD symptoms by increasing levels of the chemicals noradrenaline and dopamine that pass messages between brain cells. prescribed stimulants are methylphenidate as well as the atomoxetine. Finding the right dose and dosage will require a lot of trial and trial and. Communication with your doctor should be open and honest. Stimulants The stimulant medications prescribed for ADHD increase levels of the hormones dop