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0512 per DBT volume at a sensitivity of 90%. This also proved that making full use of 3D contextual information of DBT volume can improve the performance of the classification algorithm.Automated retinal vessel segmentation is among the most significant application and research topics in ophthalmologic image analysis. Deep learning based retinal vessel segmentation models have attracted much attention in the recent years. However, current deep network designs tend to predominantly focus on vessels which are easy to segment, while overlo