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Treatment of Add in Adults Treatment of Add in adults usually involves a combination of medication, life-skills training, and psychotherapy. Most patients respond to stimulant medications such as methylphenidate (Ritalin), and amphetamines like the lisdexamphetamine (Adderall XR), or extended-release mixed amphetamine salts. Stimulants may increase blood pressure and heart rate. Non-stimulants like atomoxetine and bupropion may also help improve ADHD symptoms.